Liver Cancer Research
A Snapshot of Liver Cancers
Information on trends in incidence, mortality, and NCI funding for liver and bile duct cancers; examples of related NCI initiatives and selected research advances.
Investigators discover new gene that affects clearance of hepatitis C virus
Scientists have discovered a new human interferon gene, Interferon Lambda 4 (IFNL4), that affects clearance of the hepatitis C virus. They also identified an inherited genetic variant within IFNL4 that predicts how people respond to treatment for hepatitis C infection.
Combining Angiogenesis-Targeted Treatments for Liver Cancer
In this trial, patients with unresectable hepatocellular carcinoma who are ineligible for a liver transplant or other local therapies will be given oral sorafenib at the standard approved dose and intravenous TRC105.
Combining Systemic Therapies for Patients with Advanced Liver Cancer
In this phase III trial, patients with unresectable, locally advanced or metastatic primary liver cancer who have good liver function (Child-Pugh score A) will receive sorafenib and be randomly assigned to also receive either doxorubicin or no additional therapy.