Liver Cancer Research

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  • A Snapshot of Liver Cancers

    Information on trends in incidence, mortality, and NCI funding for liver and bile duct cancers; examples of related NCI initiatives and selected research advances.

  • Investigators discover new gene that affects clearance of hepatitis C virus

    Scientists have discovered a new human interferon gene, Interferon Lambda 4 (IFNL4), that affects clearance of the hepatitis C virus. They also identified an inherited genetic variant within IFNL4 that predicts how people respond to treatment for hepatitis C infection.

  • Combining Angiogenesis-Targeted Treatments for Liver Cancer

    In this trial, patients with unresectable hepatocellular carcinoma who are ineligible for a liver transplant or other local therapies will be given oral sorafenib at the standard approved dose and intravenous TRC105.

  • Combining Systemic Therapies for Patients with Advanced Liver Cancer

    In this phase III trial, patients with unresectable, locally advanced or metastatic primary liver cancer who have good liver function (Child-Pugh score A) will receive sorafenib and be randomly assigned to also receive either doxorubicin or no additional therapy.