Intraocular (Eye) Melanoma

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Intraocular melanoma is a rare disease in which cancer forms in melanocytes in the eye. Melanocytes are cells that make melanin (the pigment that gives skin and eyes their color).

Intraocular melanoma begins in the uvea. The uvea has three parts. The iris is the colored area at the front of the eye. The ciliary body is a ring of muscle tissue that changes the size of the pupil and the shape of the lens. The choroid is a layer of blood vessels that brings oxygen and nutrients to the eye. Most intraocular melanomas begin in the choroid.

There may be no early signs or symptoms of intraocular melanoma. It is sometimes found during an eye exam.

Risk factors for intraocular melanoma include having fair skin that freckles and burns easily, does not tan, or tans poorly and having blue, green, or other light-colored eyes.

Anatomy of the eye, showing the outside and inside of the eye.

Causes & Prevention

NCI does not have PDQ evidence-based information about prevention of intraocular (eye) melanoma.
More information


NCI does not have PDQ evidence-based information about screening for intraocular (eye) melanoma.
More information